[1] TAN R X, WANG J W. Steroidal Chemistry(甾体化学)[M]. Beijing:Chemical Industry Press, 2009:170-174.
[2] CUI J G, LIU L, HUANG Y M. Synthesis and biological activity of steroids bearing aromatic rings and heterocycles [J]. Prog Chem(化学进展), 2014, 26(2):320-333.
[3] HANSON J R. Steroids:partial synthesis in medicinal chemistry [J]. Nat Prod Rep, 2010, 27(6):887-899.
[4] JASEM Y A, THIEMANN T, GANO L, et al. Fluorinated steroids and their derivatives [J]. J Fluorine Chem, 2016, 185:48-85. doi:10.1016/j.jfluchem.2016.03.009.
[5] EL-DESOKY E S I, REYAD M, AFSAH E M, et al. Synthesis and chemical reactions of the steroidal hormone 17a-methyltestosterone [J]. Steroids, 2016, 105(3-5):68-95.
[6] SUWANDI L S, AGOSTON G E, SHAH A J H, et al. Synthesis and antitumor activities of 3-modified 2-methoxyestradiol analogs [J]. Bioorg Med Chem Lett, 2009, 19(22):6459-6462.
[7] ZEFIROV N A, ZEFIROVA O N. 2-Methoxyestradiol and its analogs. Synthesis and structure-antiproliferative activity relationship [J]. Russ J Org Chem, 2015, 51(9):1207-1216.
[8] ASIRI A M, KHAN S A. Palladium (Ⅱ) complexes of NS donor ligands derived from steroidal thiosemicarbazones as antibacterial agents [J]. Molecules, 2010, 15(7):4784-4791.
[9] HUANG S F, WANG H, HUANG Y M, et al. The syntheses of sodium 3-β-hydroxy-cholestane 3-sulfate and its analogues [J].Guangxi Sci(广西科学), 2008, 15(7):414-418.
[10] RICHMOND V, GARRIDO S G A, MURRAY A P. Synthesis and acetylcholinesterase inhibitory activity of 2β, 3α-disulfoxy-5α-cholestan-6-one [J]. Steroids, 2011, 76(10-11):1160-1165.
[11] PANCHAPAKESAN G, DHAYALAN V, MOORTHY N D, et al. Synthesis of 2-substituted 17β-hydroxy/17-methylene estratrienes and their in vitro cytotoxicity in human cancer cell cultures [J]. Steroids, 2011, 76(13):1491-1504.
[12] TAKAHASHI M, YAMASHITA K, NUMAZAWA M. Probing the binding pocket of the active site of aromatase with 2-phenylaliphatic androsta-1,4-diene-3,17-dione steroids [J]. Steroids, 2010, 75(4-5):330-337.
[13] YOUSUF S K, MAJEED R, AHMAD M, et al. Ring A structural modified derivatives of withaferin A and the evaluation of their cytotoxic potential [J]. Steroids, 2011,76(10):1213-1222.
[14] WATARI Y, YAMAGUCHI S, TAKAHASHI M, et al. 4-and 6-(p-Sulphamoylphenyl)androstenediones:studies of aromatase. inhibitor-based oestrone sulphatase inhibition [J]. Steroids, 2010, 75(12):891-896.
[15] YADAV M R, BARMADE M A, TAMBOLI R S, et al. Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer [J]. Eur J Med Chem, 2015, 105:1-38. doi:10.1016/j.ejmech.2015.09.038.
[16] KADAR Z, BAJI A, ZUPKO I, et al. Efficient approach to novel 1-triazolyl-5-androstane derivatives as potent anti-proliferative agents [J]. Org Biomol Chem, 2011, 9(23):2-9.
[17] FRANK E, SCHNEIDER G. Synthesis of sex hormone-derived modified steroids possessing antiproliferative activity [J]. J Steroid Biochem Mol Biol, 2013, 137:301-315. doi:10.1016/j.jsbmb.2013.02.018.
[18] LU X F, YANG Z, HUANG N Y, et al. Synthesis and cytotoxic activities of 2-substituted (25R)-spirostan-1,4,6-triene-3-ones via ring-opening/elimination and ‘click’ strategy [J]. Bioorg Med Chem Lett, 2015, 25(17):3726-3729.
[19] JEGHAM H, MALTAIS R, DUFOUR P, et al. Solid-phase chemical synthesis and in vitro biological evaluation of novel 2β-piperazino-(20R)-5a-pregnane-3a,20-diol N-derivatives as anti-leukemic agents [J]. Steroids, 2012, 77(13):1403-1418.
[20] YAMANSAROV E Y, KAZAKOVA O B, MEDVEDEVA N I, et al. First synthesis of steroidal 1,2,4-trioxolanes [J]. Russ J Org Chem, 2014, 50(7):1043-1047.
[21] DAS A M, HAZARIKA M P. Synthesis of some novel steroidal 1,2,4,5-tetraoxanes [J]. RSC Adv, 2015, 5(26):19818-19822.
[22] SHAMSUZZAMAN, SIDDIQUI T, ALAM M G, et al. Synthesis, characterization and anticancer studies of new steroidal oxadiazole, pyrrole and pyrazole derivatives [J]. J Saudi Chem Soc, 2015, 19(4):387-391.
[23] SHAMSUZZAMAN, BAQI K A, ALI A, et al. Synthesis, characterization, biological evaluation and molecular docking of steroidal spirothiazolidinones [J]. J Mol Struct, 2015, 1085:104-114. doi:10.1016/j.molstruc.2014.12.036.
[24] LEI M, XIAO Z Y, MA B, et al. Synthesis and biological evaluation of bufalin-3-yl nitrogen-containing-carbamate derivatives as anticancer agents [J]. Steroids, 2016, 108:56-60. doi:10.1016/j.steroids.2016.01.011.
[25] JURASEK M, DZUBAK P, SEDLAK D, et al. Preparation, preliminary screening of new types of steroid conjugates and their activities on steroid receptors [J]. Steroids, 2013, 78(3):356-361.
[26] LIU L, JIA L Y, HUANG Y M, et al. Synthesis of 3-substituted pregn-4-en-6, 20-diones containing nitrogen [J]. Chem Reagents(化学试剂), 2013, 35(4):309-312.
[27] VARELA C, ELISIARIO J, SILVA T D, et al. New structure-activity relationships of a-and d-ring modified steroidal aromatase inhibitors:design synthesis, and biochemical evaluation [J]. J Med Chem, 2012, 55(8):3992-4002.
[28] SAKAC M, GAKOVIC A, DJURENDIC E, et al. Synthesis and biological evaluation of a series of A, B-ring modified 16,17-secoandrostane derivatives [J]. Bioorg Chem, 2008, 36(3):128-132.
[29] YADVA M R, SABALE P M, GIRIDHAR R, et al. Steroidal carbonitriles as potential aromatase inhibitors [J]. Steroids, 2012, 77(8):850-857.
[30] MOSTAFA Y A, KRALT B, TAYLOR S D, et al. A-ring substituted 17β-arylsulfonamides of 17β-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase [J]. Bioorg Med Chem, 2015, 23(17):5681-5692.
[31] KIURU P S, WAHALA K. Short synthesis of 2-methoxyestradiol and 2-hydroxyestradiol [J]. Steroids, 2003, 68(4):373-375.
[32] KIM S, KIM Y U, MA E. Synthesis and 5α-reductase inhibitory activity of c21 steroids having 1,4-diene or 4,6-diene 20-ones and 4-azasteroid 20-oximes [J]. Molecules, 2012, 17(1):355-368.
[33] HUANG Y M, CUI J, CHEN, et al. Synthesis and antiproliferative activity of some steroidal lactams [J]. Steroids, 2011, 76(12):1346-1350.
[34] EL-FAR M, ELMEGEED G A, ESKANDER E F, et al. Novel modified steroid derivatives of androstanolone as chemotherapeutic anti-cancer agents [J]. Eur J Med Chem, 2009, 44(10):3936-3946.
[35] GOGOI S, SHEKARRAO K, DUARAH A, et al. A microwave promoted solvent-free approach to steroidal quinolines and their in vitro evaluation for antimicrobial activities [J]. Steroids, 2012, 77(13):1438-1445.
[36] BAJI A, GYOVAI A, WOLFLING J, et al. Microwave-assisted one-pot synthesis of steroid-quinoline hybrids and an evaluation of their antiproliferative activities on gynecological cancer cell lines [J]. RSC Adv, 2016, 6(33):27501-27516.
[37] YADAV M R, SABALE P M, GIRIDHAR, et al. Synthesis of some novel androstanes as potential aromatase inhibitors [J]. Steroids, 2011, 76(5):464-470.
[38] LAURO F V, FRANCISCO D C, ELODIA G C, et al. Synthesis and antibacterial activity evaluation of two androgen derivatives [J]. Steroids, 2015,93(suppl C):8-15.